Publikationen

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MMRS

Process Intensification of the catalytic hydrogenation of squalene using a Pd/CNT catalyst combining nanoparticles and single atoms in a continuous flow reactorChem. Eng. J., 2022, 441, 135951

Gas-liquid flow patterns in a rectangular milli-structured channel with static mixing elements
Chem. Eng. Technol. 10.1002/ceat.202100355, Article ASAP

Scalable continuous flow hydrogenations using Pd/Al2O3-coated rectangular cross-section 3D-printed static mixers
Catal. Today, 2022, 383, 55-63

Telescoped Lithiation, CArylation and Methoxylation in Flow-Batch Hybrid toward the Synthesis of Canagliflozin
Tetrahedron Let., 2021, 82, 153351

Process intensification of ozonolysis reactions using dedicated microstructured reactors
React. Chem. Eng., 2021, 6, 2253-2258

CFD analysis of asymmetric mixing at different inlet configurations of a split-and-recombine micro mixer
J. Flow. Chem. 2021, 11, 599-609

Flash Chemistry Approach to Organometallic C‑Glycosylation for the Synthesis of Remdesivir
Org. Process Res. Dev. 2021, 25, 4, 1015-1021

Advanced Real-Time Process Analytics for Multistep Synthesis in Continuous Flow
Angew. Chem. Int. Ed. 2021, 60, 2-12, “Very Important Paper”

Organomagnesium Based Flash Chemistry: Continuous Flow Generation and Utilization of Halomethylmagnesium Intermediates
Org. Lett. 2020, 22, 7537−7541

Optimization and Scale-Up of the Continuous Flow Acetylation and Nitration of 4‑Fluoro-2-methoxyaniline to Prepare a Key Building Block of Osimertinib
Org. Process Res. Dev. 2020, 24, 2217-2227

Synthesis of N-vinyl pyrrolidone by acetylene process in a microreactor
CET Advances, 2020, 2, 100018

Continuous Flow C-Glycosylation via Metal–Halogen Exchange: Process Understanding and Improvements toward Efficient Manufacturing of Remdesivir
Org. Process Res. Dev. 2020, 24, 10, 2362-2368

Oxidative Esterification of 5-Hydroxymethylfurfural under Flow Conditions Using a Bimetallic Co/Ru Catalyst
ChemCatChem 2020, 12, 3504-3511

Multivariate analysis of inline benchtop NMR data enables rapid optimization of a complex nitration in flow
React. Chem. Eng. 2020,5, 677-684

Preparation of highly active phosphated TiO2 catalysts via continuous sol-gel synthesis in a microreactor
Catal. Sci. Technol, 2019, 9, 4744

Fouling of Flow Reactors in Organolithium Mediated Transformations: Experience on Scale-up and Proposed Solution
CHIMIA 2019, 73, No. 10, 809-816

Experimental Methods in Chemical Engineering: Micro‐Reactors
Can. J. Chem. Eng. 2019, 97, 2578-2587

Laboratory of the future: a modular flow platform with multiple integrated PAT tools for multistep reactions
React. Chem. Eng., 2019, 4, 1571-1578

Biphasic short time heat degradation of the blue microalgae protein phycocyanin from Arthrospira platensis
Innovative Food Science & Emerging Technologies, 2019, 52, 116-121

Perspective of Micro Process engineering for thermal Food treatment
Front. Nutr., 2018, 5, 24

Mixing Performance Evaluation for Commercially Available Micromixers Using Villermaux−Dushman Reaction Scheme with the Interaction by Exchange with the Mean Model
Org. Process Res. Dev. 2017, 21, 816−820

Continuous Cocrystallization of Benzoic Acid and Isonicotinamide by Mixing-Induced Supersaturation: Exploring Opportunities between Reactive and Antisolvent Crystallization Concepts
Cryst. Growth Des. 2017, 17, 1902−1909

Precipitation in a Micromixer – From Laboratory to Industrial Scale
Chem. Eng. Technol. 2015, 38, No. 11, 2017–2024

NUOVE TECNOLOGIE PER LA SINTESI DI API (in Italian)
Chimica & Tecnologia, 2015, 5, 33-38

FIMOR: An efficient simulation for ZnO quantum dot ripening applied to the optimization of nanoparticle synthesis
Chemical Engineering Journal 260 (2015) 706–715

Microreactor as efficient tool for light induced oxidation reactions
Chemical Engineering Journal 255 (2014) 178–184

Continuous precipitation of Cu/ZnO/Al2O3 catalysts for methanol synthesis in microstructured reactors with alternative precipitating agents
Applied Catalysis A: General 450 (2013) 1–12

Single Pellet String Reactor for Intensification of Catalyst Testing in Gas/Liquid/Solid Configuration
Oil & Gas Science and Technology – Rev. IFP Energies nouvelles, Vol. 65 (2010), No. 5

µ-Consortium: Aufbau einer mobilen Anlage für die Aus- und Weiterbildung in der Mikroverfahrenstechnik (in German)
Chem. Ing. Tech. 2010, 82, No. 10, 1799-1806

Experimental Investigation and Modeling Approach of the Phenylacetonitrile Alkylation Process in a Microreactor
Chem. Eng. Technol. 2009, 32, No. 6, 919–925

Investigation of the Moffatt-Swern Oxidation in a Continuous Flow Microreactor System
Organic Process Research & Development 2008, 12, 911–920

FlowPlate®

Scale-up of micro- and milli-reactors: An overview of strategies, design principles and applications

Chemical Engineering Science: X 10, 2021, 100097

 

Telescoped Lithiation, CArylation and Methoxylation in Flow-Batch Hybrid toward the Synthesis of Canagliflozin

Tetrahedron Let., 2021, 82, 153351

 

Process intensification of ozonolysis reactions using dedicated microstructured reactors

React. Chem. Eng., 2021, 6, 2253-2258

 

Flash Chemistry Approach to Organometallic C‑Glycosylation for the Synthesis of Remdesivir

Org. Process Res. Dev. 2021, 25, 4, 1015-1021

 

Advanced Real-Time Process Analytics for Multistep Synthesis in Continuous Flow

Angew. Chem. Int. Ed. 2021, 60, 2-12, “Very Important Paper”

 

Organomagnesium Based Flash Chemistry: Continuous Flow Generation and Utilization of Halomethylmagnesium Intermediates

Org. Lett. 2020, 22, 7537−7541

 

Optimization and Scale-Up of the Continuous Flow Acetylation and Nitration of 4‑Fluoro-2-methoxyaniline to Prepare a Key Building Block of Osimertinib

Org. Process Res. Dev. 2020, 24, 2217-2227

 

Continuous Flow C-Glycosylation via Metal–Halogen Exchange: Process Understanding and Improvements toward Efficient Manufacturing of Remdesivir

Org. Process Res. Dev. 2020, 24, 10, 2362-2368

 

Multivariate analysis of inline benchtop NMR data enables rapid optimization of a complex nitration in flow

React. Chem. Eng. 2020,5, 677-684

 

Fouling of Flow Reactors in Organolithium Mediated Transformations: Experience on Scale-up and Proposed Solution

CHIMIA 2019, 73, No. 10, 809-816

 

Experimental Methods in Chemical Engineering: Micro‐Reactors

Can. J. Chem. Eng. 2019, 97, 2578-2587

 

Laboratory of the future: a modular flow platform with multiple integrated PAT tools for multistep reactions

React. Chem. Eng., 2019, 4, 1571-1578

 

Continuous-Flow Difluoromethylation with Chlorodifluoromethane under Biphasic Conditions

J. Flow Chem. 2017, 7(2), 46–51

 

Mixing Performance Evaluation for Commercially Available Micromixers Using Villermaux−Dushman Reaction Scheme with the Interaction by Exchange with the Mean Model

Org. Process Res. Dev. 2017, 21, 816−820

 

Liquid–liquid flow regimes and mass transfer in various micro-reactors

Chemical Engineering Journal 300 (2016) 9–19

 

Microreactor mixing-unit design for fast liquid—liquid reactions

J. Flow Chem. 2016, 6(3), 279 – 287

 

Liquid–liquid mass transfer in a serpentine micro-reactor using various Solvents

Chemical Engineering Journal 285 (2016) 605–615

 

On the scale-up of micro-reactors for liquid–liquid reactions

Chemical Engineering Science143(2016) 216–225

 

From Batch to Continuous Chemical Synthesis – A Toolbox Approach

Org. Process Res. Dev. 2014, 18, 1286−1294

 

Control of Hazardous Processes in Flow: Synthesis of 2-Nitroethanol

J. Flow Chem. 2014, 4, 26–34

 

The past, present and potential for microfluidic reactor technology in chemical synthesis

Nature Chemistry volume 5, pages 905–915 (2013)

 

Pressure drop and mixing in single phase microreactors: Simplified designs of Micromixers

Chemical Engineering and Processing 50 (2011) 1069–1075

 

Harsh Reaction Conditions in Continuous-Flow Microreactors for Pharmaceutical Production

Chem. Eng. Technol. 2009, 32, No. 11, 1682–1694

 

Microreactor Technology: A Revolution for the Fine Chemical and Pharmaceutical Industries?

Chem. Eng. Technol. 2005, 28, No. 3

ART®

Mixing Performance in a Distributed-Feed Plate-Type Reactor with Multinozzle Injection for Fine Chemical Production Scale
Ind. Eng. Chem. Res. 2020, 59, 9, 3655-3668

Characterization of a Modular, Scalable Millistructured Plate Reactor
Chem. Ing. Tech. 2019, 91, No. 5, 602-606

Development of a Grignard-Type Reaction for Manufacturing in a Continuous-Flow Reactor
Org. Process Res. Dev., 2014, 18 (11), pp 1545–1549

Ehrfeld Reactors
SCALABLE FLOW REACTORS FOR INDUSTRY
Chimica & Tecnologia, 2018, 4, 34-37

Miprowa®

Process Intensification of the catalytic hydrogenation of squalene using a Pd/CNT catalyst combining nanoparticles and single atoms in a continuous flow reactorChem. Eng. J., 2022, 441, 135951

 

Gas-liquid flow patterns in a rectangular milli-structured channel with static mixing elements

Chem. Eng. Technol. 10.1002/ceat.202100355, Article ASAP

 

Scalable continuous flow hydrogenations using Pd/Al2O3-coated rectangular cross-section 3D-printed static mixers

Catal. Today, 2022, 383, 55-63

 

Scale-up of micro- and milli-reactors: An overview of strategies, design principles and applications

Chemical Engineering Science: X 10, 2021, 100097

 

Advanced Real-Time Process Analytics for Multistep Synthesis in Continuous Flow

Angew. Chem. Int. Ed. 2021, 60, 2-12, “Very Important Paper”

 

Synthesis of N-vinyl pyrrolidone by acetylene process in a microreactor

CET Advances, 2020, 2, 100018

 

Einfluss mikrostrukturierter statischer Mischer auf den Gas/Flüssig-Stofftransport in einem engen Rechteckkanal (in German)

Chem. Ing. Tech. 2019, 91, No. 5, 614-621

 

Experimentelle Bestimmung des konvektiven Wärmeübergangs in einem mikrostrukturierten Kanal (in German)

Chem. Ing. Tech. 2017, 89, No. 4, 379–389

 

CHINA – SUCCESSFUL EXECUTION OF TECHNICAL PROJECTS

VDMA impulse 4/2017

 

Compact Heat Exchangers: Designs, Materials and Applications

ISBN 3-934736-42-4

 

On the scale-up of micro-reactors for liquid–liquid reactions

Chemical Engineering Science143(2016)216–225

Influence of Design Parameters on Hydrodynamics and Heat Transfer of a Modularized Millireactor

Chem. Eng. Technol. 2015, 38, No. 00, 1–8

 

NUOVE TECNOLOGIE PER LA SINTESI DI API (in Italian)

Chimica & Tecnologia, 2015, 5, 33-38

Ehrfeld Reactors
SCALABLE FLOW REACTORS FOR INDUSTRY
Chimica & Tecnologia, 2018, 4, 34-37